mouse SLC24A2 shRNA silencing AAV

Name
AAV-m-SLC24A2-shRNA

Cat No
shAAV-272177

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Slc24a2.

shAAV-272177

AAV-m-SLC24A2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Slc24a2 (solute carrier family 24 (sodium/potassium/calcium exchanger), member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2810021B17Rik; 6330417K15Rik; AI847460; Nckx2

Description (Vector)

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).

Gene ID

76376

Gene Name (Vector)

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

Gene Symbol

Slc24a2

ORF Size (aa)

2136

ORF Size (bp)

2136 bp

RefSeq ID

NM_172426

RefSeq Synonyms

NM_172426, NM_001110240, BC116637, BC115867,

Species

mouse

UniGene ID

Mm.127296

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.