mouse SLC22A2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Slc22a2.
shAAV-272153
AAV-m-SLC22A2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Slc22a2 (solute carrier family 22 (organic cation transporter), member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Oct2; Orct2
Description (Vector)
Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.
Gene ID
20518
Gene Name (Vector)
solute carrier family 22 (organic cation transporter), member 2
Gene Symbol
Slc22a2
ORF Size (aa)
1662
ORF Size (bp)
1662 bp
RefSeq ID
NM_013667
RefSeq Synonyms
NM_013667, BC069911, BC015250,
Species
mouse
UniGene ID
Mm.17322
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.
