mouse SLC22A17 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Slc22a17.
shAAV-272150
AAV-m-SLC22A17-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Slc22a17 (solute carrier family 22 (organic cation transporter), member 17). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700094C23Rik; 24p3R; AU041908; AW555662; Boct; BOIT
Description (Vector)
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).
Gene ID
59049
Gene Name (Vector)
solute carrier family 22 (organic cation transporter), member 17
Gene Symbol
Slc22a17
ORF Size (aa)
948
ORF Size (bp)
948 bp
RefSeq ID
NM_021551
RefSeq Synonyms
NM_021551, BC062878,
Species
mouse
UniGene ID
Mm.27435
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.