mouse SH2D4A shRNA silencing AAV

Name
AAV-m-SH2D4A-shRNA

Cat No
shAAV-271886

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Sh2d4a.

shAAV-271886

AAV-m-SH2D4A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sh2d4a (SH2 domain containing 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2210402M20Rik; SH2A

Description (Vector)

Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

Gene ID

72281

Gene Name (Vector)

SH2 domain containing 4A

Gene Symbol

Sh2d4a

ORF Size (aa)

1266

ORF Size (bp)

1266 bp

RefSeq ID

NM_028182

RefSeq Synonyms

NM_028182, BC116682,

Species

mouse

UniGene ID

Mm.40974

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.