mouse SH2D1A shRNA silencing AAV

Name 
AAV-m-SH2D1A-shRNA
Cat No 
shAAV-271877
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sh2d1a.

shAAV-271877
AAV-m-SH2D1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sh2d1a (SH2 domain containing 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gm686; SAP
Description (Vector)
Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
Gene ID
20400
Gene Name (Vector)
SH2 domain containing 1A
Gene Symbol
Sh2d1a
ORF Size (aa)
246
RefSeq ID
NM_011364
RefSeq Synonyms
NM_011364, NM_001313691, NM_001313689, NM_001313688, BC147811, BC147807, BC147368, BC147367,
Species
mouse
UniGene ID
Mm.441197

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.