mouse SF3B2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sf3b2.
shAAV-271782
AAV-m-SF3B2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sf3b2 (splicing factor 3b, subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; SAP145; SF3b1; SF3b145; SF3b150
Description (Vector)
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Gene ID
319322
Gene Name (Vector)
splicing factor 3b, subunit 2
Gene Symbol
Sf3b2
ORF Size (aa)
2637
ORF Size (bp)
2637 bp
RefSeq ID
NM_030109
RefSeq Synonyms
NM_030109, BC049118,
Species
mouse
UniGene ID
Mm.471551
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.