mouse SARM1 shRNA silencing AAV

Name 
AAV-m-SARM1-shRNA
Cat No 
shAAV-271364
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sarm1.

shAAV-271364
AAV-m-SARM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sarm1 (sterile alpha and HEAT/Armadillo motif containing 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A830091I15Rik; C78606; MyD885; Sarm
Description (Vector)
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
Gene ID
237868
Gene Name (Vector)
sterile alpha and HEAT/Armadillo motif containing 1
Gene Symbol
Sarm1
ORF Size (aa)
2175
ORF Size (bp)
2175 bp
RefSeq ID
NM_172795
RefSeq Synonyms
NM_172795, NM_001168521, BC080850, BC058534,
Species
mouse
UniGene ID
Mm.210332

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.