mouse RTN4R shRNA silencing AAV

Name 
AAV-m-RTN4R-shRNA
Cat No 
shAAV-271224
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rtn4r.

shAAV-271224
AAV-m-RTN4R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rtn4r (reticulon 4 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NgR; NgR1; NOGOR
Description (Vector)
Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity).
Gene ID
65079
Gene Name (Vector)
reticulon 4 receptor
Gene Symbol
Rtn4r
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
RefSeq ID
NM_022982
RefSeq Synonyms
NM_022982, BC058381, BC052317,
Species
mouse
UniGene ID
Mm.40149

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.