mouse RTEL1 shRNA silencing AAV

Name 
AAV-m-RTEL1-shRNA
Cat No 
shAAV-271210
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rtel1.

shAAV-271210
AAV-m-RTEL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rtel1 (regulator of telomere elongation helicase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI451565; AW540478; Rtel
Description (Vector)
ATP-dependent DNA helicase required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by promoting the disassembly of D loop recombination intermediates. Also required to regulate telomere length; probably due to its anti-recombinase function.
Gene ID
269400
Gene Name (Vector)
regulator of telomere elongation helicase 1
Gene Symbol
Rtel1
ORF Size (aa)
3495
ORF Size (bp)
3495 bp
RefSeq ID
NM_001001882
RefSeq Synonyms
NM_001166668, NM_001166667, NM_001166666, NM_001166665, NM_001001882, BC145658, BC144978, BC144977, BC105578,
Species
mouse
UniGene ID
Mm.11333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.