mouse RSPO3 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-271188
Availability:
6-8 weeks
Name:
AAV-m-RSPO3-shRNA
This is an AAV expressing shRNA for silencing of Mouse Rspo3.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Rspo3
- Gene Name
- R-spondin 3
- Gene ID
- 72780
- Gene Synonyms
- 2810459H04Rik; AW742308; Cristin1; Thsd2
- ORF Size
- 834 bp
- RefSeq#
- NM_028351
- Gene Description
- Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway (By similarity).
- UniGene ID
- Mm.45191
Related Products
Product | Cat No. |
---|---|
AAV-h-RSPO3 | AAV-222066 |
AAV-m-RSPO3 | AAV-271188 |
Ad-h-RSPO3 | ADV-222066 |
Ad-m-RSPO3 | ADV-271188 |
AAV-h-RSPO3-shRNA | shAAV-222066 |
Ad-h-RSPO3-shRNA | shADV-222066 |
Ad-m-RSPO3-shRNA | shADV-271188 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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