mouse RSAD2 shRNA silencing AAV

Name
AAV-m-RSAD2-shRNA

Cat No
shAAV-271168

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Rsad2.

shAAV-271168

AAV-m-RSAD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rsad2 (radical S-adenosyl methionine domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2510004L01Rik; cig5; Vig1

Description (Vector)

Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.

Gene ID

58185

Gene Name (Vector)

radical S-adenosyl methionine domain containing 2

Gene Symbol

Rsad2

ORF Size (aa)

1089

ORF Size (bp)

1089 bp

RefSeq ID

NM_021384

RefSeq Synonyms

NM_021384, BC057868,

Species

mouse

UniGene ID

Mm.24045

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.