mouse RP1 shRNA silencing AAV

Name
AAV-m-RP1-shRNA

Cat No
shAAV-270794

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Rp1.

shAAV-270794

AAV-m-RP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rp1 (retinitis pigmentosa 1 (human)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Dcdc3; mG145; Orp1; Rp1h

Description (Vector)

Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher order stacking of outer segment disks along the photoreceptor axoneme (By similarity).

Gene ID

19888

Gene Name (Vector)

retinitis pigmentosa 1 (human)

Gene Symbol

Rp1

ORF Size (aa)

6288

ORF Size (bp)

6288 bp

RefSeq ID

NM_011283

RefSeq Synonyms

NM_011283, NM_001195662, BC120928, BC120927,

Species

mouse

UniGene ID

Mm.294263

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.