mouse RCC1 shRNA silencing AAV

Name 
AAV-m-RCC1-shRNA
Cat No 
shAAV-270315
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rcc1.

shAAV-270315
AAV-m-RCC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rcc1 (regulator of chromosome condensation 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4931417M11Rik; AI326872; Chc1
Description (Vector)
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Gene ID
100088
Gene Name (Vector)
regulator of chromosome condensation 1
Gene Symbol
Rcc1
ORF Size (aa)
1305
ORF Size (bp)
1305 bp
RefSeq ID
NM_133878
RefSeq Synonyms
NM_133878, NM_001197082, BC057645, BC019807,
Species
mouse
UniGene ID
Mm.255045

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.