mouse RASSF5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rassf5.
shAAV-270201
AAV-m-RASSF5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rassf5 (Ras association (RalGDS/AF-6) domain family member 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300019G20Rik; Maxp1; Nore1; Nore1A; Nore1B; Rapl
Description (Vector)
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.
Gene ID
54354
Gene Name (Vector)
Ras association (RalGDS/AF-6) domain family member 5
Gene Symbol
Rassf5
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_018750
RefSeq Synonyms
NM_018750, NM_001313731, NM_001311094, BC089605,
Species
mouse
UniGene ID
Mm.248291
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.