mouse RASIP1 shRNA silencing AAV

Name
AAV-m-RASIP1-shRNA

Cat No
shAAV-270181

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Rasip1.

shAAV-270181

AAV-m-RASIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rasip1 (Ras interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1110025D03Rik; 2610025P08Rik; AI853551; Rain

Description (Vector)

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Gene ID

69903

Gene Name (Vector)

Ras interacting protein 1

Gene Symbol

Rasip1

ORF Size (aa)

2886

ORF Size (bp)

2886 bp

RefSeq ID

NM_028544

RefSeq Synonyms

NM_028544, BC150766, BC127059,

Species

mouse

UniGene ID

Mm.181396

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.