mouse RAD51L1 shRNA silencing AAV

Name 
AAV-m-RAD51L1-shRNA
Cat No 
shAAV-270066
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rad51b.

shAAV-270066
AAV-m-RAD51L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rad51b (RAD51 paralog B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI553500; mREC2; R51H2; Rad51l1
Description (Vector)
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Gene ID
19363
Gene Name (Vector)
RAD51 paralog B
Gene Symbol
Rad51b
ORF Size (aa)
747
ORF Size (bp)
747 bp
RefSeq ID
NM_009014
RefSeq Synonyms
NM_009014, NM_001252562, BC058184,
Species
mouse
UniGene ID
Mm.341756

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.