mouse QPCT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Qpct.
shAAV-269917
AAV-m-QPCT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Qpct (glutaminyl-peptide cyclotransferase (glutaminyl cyclase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5730422A13Rik
Description (Vector)
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.
Gene ID
70536
Gene Name (Vector)
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
Gene Symbol
Qpct
ORF Size (aa)
1089
ORF Size (bp)
1089 bp
RefSeq ID
NM_001316729
RefSeq Synonyms
NM_027455, NM_001316729, BC151029, BC151027, BC020023,
Species
mouse
UniGene ID
Mm.293870
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.