mouse PSMB5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Psmb5.
shAAV-269638
AAV-m-PSMB5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Psmb5 (proteasome (prosome, macropain) subunit, beta type 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage through the Nrf2-ARE pathway (By similarity).
Gene ID
19173
Gene Name (Vector)
proteasome (prosome, macropain) subunit, beta type 5
Gene Symbol
Psmb5
ORF Size (aa)
795
RefSeq ID
NM_011186
RefSeq Synonyms
NM_011186, BC106144, BC012246,
Species
mouse
UniGene ID
Mm.8911
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.