mouse PRKRIR shRNA silencing AAV

Name 
AAV-m-PRKRIR-shRNA
Cat No 
shAAV-269396
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Thap12.

shAAV-269396
AAV-m-PRKRIR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Thap12 (THAP domain containing 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
57
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2900052B10Rik; Dap4; Prkrir; Rpkrir
Description (Vector)
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Gene ID
72981
Gene Name (Vector)
THAP domain containing 12
Gene Symbol
Thap12
ORF Size (aa)
2277
ORF Size (bp)
2277 bp
RefSeq ID
NM_028410
RefSeq Synonyms
NM_028410, BC049103,
Species
mouse
UniGene ID
Mm.4428

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.