mouse PRDM5 shRNA silencing AAV

Name 
AAV-m-PRDM5-shRNA
Cat No 
shAAV-269311
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Prdm5.

shAAV-269311
AAV-m-PRDM5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Prdm5 (PR domain containing 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4432417F03Rik; 6530401I24Rik; AI197291; E130112L17Rik; PFM2
Description (Vector)
Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.
Gene ID
70779
Gene Name (Vector)
PR domain containing 5
Gene Symbol
Prdm5
ORF Size (aa)
1800
ORF Size (bp)
1800 bp
RefSeq ID
NM_027547
RefSeq Synonyms
NM_029549, NM_027547, BC138902, BC138901,
Species
mouse
UniGene ID
Mm.263355

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.