mouse PRC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Prc1.
shAAV-269301
AAV-m-PRC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Prc1 (protein regulator of cytokinesis 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D7Ertd348e
Description (Vector)
Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.
Gene ID
233406
Gene Name (Vector)
protein regulator of cytokinesis 1
Gene Symbol
Prc1
ORF Size (aa)
1812
ORF Size (bp)
1812 bp
RefSeq ID
NM_145150
RefSeq Synonyms
NM_145150, NM_001285998, NM_001285997, BC005475,
Species
mouse
UniGene ID
Mm.227274
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.