mouse PPP1R1A shRNA silencing AAV

Name 
AAV-m-PPP1R1A-shRNA
Cat No 
shAAV-269206
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppp1r1a.

shAAV-269206
AAV-m-PPP1R1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp1r1a (protein phosphatase 1, regulatory (inhibitor) subunit 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610038N18Rik; I-1
Description (Vector)
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Gene ID
58200
Gene Name (Vector)
protein phosphatase 1, regulatory (inhibitor) subunit 1A
Gene Symbol
Ppp1r1a
ORF Size (aa)
516
RefSeq ID
NM_021391
RefSeq Synonyms
NM_021391, BC025123,
Species
mouse
UniGene ID
Mm.143788

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.