mouse PPP1CB shRNA silencing AAV

Name
AAV-m-PPP1CB-shRNA

Cat No
shAAV-269185

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Ppp1cb.

shAAV-269185

AAV-m-PPP1CB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp1cb (protein phosphatase 1, catalytic subunit, beta isoform). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1200010B19

Description (Vector)

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Gene ID

19046

Gene Name (Vector)

protein phosphatase 1, catalytic subunit, beta isoform

Gene Symbol

Ppp1cb

ORF Size (aa)

984

ORF Size (bp)

984 bp

RefSeq ID

NM_172707

RefSeq Synonyms

NM_172707, BC046832,

Species

mouse

UniGene ID

Mm.456635

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.