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mouse POLR2C shRNA silencing AAV

Name 
AAV-m-POLR2C-shRNA
Cat No 
shAAV-269034
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Polr2c.

shAAV-269034
AAV-m-POLR2C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Polr2c (polymerase (RNA) II (DNA directed) polypeptide C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
33kDa; mRBP31; RPB3; Rpo2-3
Description (Vector)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).
Gene ID
20021
Gene Name (Vector)
polymerase (RNA) II (DNA directed) polypeptide C
Gene Symbol
Polr2c
ORF Size (aa)
828
ORF Size (bp)
828 bp
RefSeq ID
NM_009090
RefSeq Synonyms
NM_009090, BC099548, BC002023,
Species
mouse
UniGene ID
Mm.292492

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.