mouse PLXNA4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Plxna4.
shAAV-268917
AAV-m-PLXNA4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Plxna4 (plexin A4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9330117B14; mKIAA1550; Plxa4
Description (Vector)
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
Gene ID
243743
Gene Name (Vector)
plexin A4
Gene Symbol
Plxna4
ORF Size (aa)
5673
ORF Size (bp)
5673 bp
RefSeq ID
NM_175750
RefSeq Synonyms
NM_175750, BC141298,
Species
mouse
UniGene ID
Mm.444029
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.