mouse PLA1A shRNA silencing AAV

Name
AAV-m-PLA1A-shRNA

Cat No
shAAV-268752

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Pla1a.

shAAV-268752

AAV-m-PLA1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pla1a (phospholipase A1 member A). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AA986889; Ps-pla1; Pspla1

Description (Vector)

Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.

Gene ID

85031

Gene Name (Vector)

phospholipase A1 member A

Gene Symbol

Pla1a

ORF Size (aa)

1371

ORF Size (bp)

1371 bp

RefSeq ID

NM_134102

RefSeq Synonyms

NM_134102, BC030670, BC003470,

Species

mouse

UniGene ID

Mm.279805

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.