mouse PIKFYVE shRNA silencing AAV

Name 
AAV-m-PIKFYVE-shRNA
Cat No 
shAAV-268659
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pikfyve.

shAAV-268659
AAV-m-PIKFYVE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pikfyve (phosphoinositide kinase, FYVE finger containing). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5230400C17Rik; p235; Pip5k; Pip5k3; Pipk5k3; PipkIII
Description (Vector)
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Gene ID
18711
Gene Name (Vector)
phosphoinositide kinase, FYVE finger containing
Gene Symbol
Pikfyve
ORF Size (aa)
6156
ORF Size (bp)
6156 bp
RefSeq ID
NM_011086
RefSeq Synonyms
NM_011086, NM_001310624, BC148367,
Species
mouse
UniGene ID
Mm.38370

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.