mouse PICALM shRNA silencing AAV

Name 
AAV-m-PICALM-shRNA
Cat No 
shAAV-268603
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Picalm.

shAAV-268603
AAV-m-PICALM-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Picalm (phosphatidylinositol binding clathrin assembly protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CALM; CLTH; fit-1; fit1; mKIAA4114; PAP180
Description (Vector)
Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.
Gene ID
233489
Gene Name (Vector)
phosphatidylinositol binding clathrin assembly protein
Gene Symbol
Picalm
ORF Size (aa)
1959
ORF Size (bp)
1959 bp
RefSeq ID
NM_146194
RefSeq Synonyms
NM_146194, NM_001252524, NM_001252523, NM_001252522, NM_001252521, NM_001252520, BC057683, BC025566, BC023843, BC021491, BC011470,
Species
mouse
UniGene ID
Mm.393563

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.