mouse PER1 shRNA silencing AAV

Name 
AAV-m-PER1-shRNA
Cat No 
shAAV-268400
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Per1.

shAAV-268400
AAV-m-PER1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Per1 (period circadian clock 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hftm; m-rigui; mPer1; Per
Description (Vector)
Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. Can bind heme (By similarity).
Gene ID
18626
Gene Name (Vector)
period circadian clock 1
Gene Symbol
Per1
ORF Size (aa)
3558
ORF Size (bp)
3558 bp
RefSeq ID
NM_011065
RefSeq Synonyms
NM_011065, NM_001159367, BC091645, BC039768,
Species
mouse
UniGene ID
Mm.7373

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.