mouse PELI3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Peli3.
shAAV-268389
AAV-m-PELI3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Peli3 (pellino 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6030441F14Rik; A930011L17; BC028931
Description (Vector)
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.
Gene ID
240518
Gene Name (Vector)
pellino 3
Gene Symbol
Peli3
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_172835
RefSeq Synonyms
NM_172835, NM_001347422, BC028931,
Species
mouse
UniGene ID
Mm.277580
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.