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mouse PDLIM5 shRNA silencing AAV

Name 
AAV-m-PDLIM5-shRNA
Cat No 
shAAV-268341
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pdlim5.

shAAV-268341
AAV-m-PDLIM5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pdlim5 (PDZ and LIM domain 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110001A05Rik; AI987914; C87059; Enh; Enh1; Enh2; Enh3; LIM
Description (Vector)
PDLIM5 may play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity).
Gene ID
56376
Gene Name (Vector)
PDZ and LIM domain 5
Gene Symbol
Pdlim5
ORF Size (aa)
1776
ORF Size (bp)
1776 bp
RefSeq ID
NM_019809
RefSeq Synonyms
NM_022554, NM_019809, NM_019808, NM_001190857, NM_001190856, NM_001190855, NM_001190854, NM_001190853, NM_001190852, BC037476,
Species
mouse
UniGene ID
Mm.117709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.