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mouse PCBD2 shRNA silencing AAV

Name 
AAV-m-PCBD2-shRNA
Cat No 
shAAV-268139
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pcbd2.

shAAV-268139
AAV-m-PCBD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pcbd2 (pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2700061N24Rik; Dcoh2; Dcohm
Description (Vector)
Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity)|Function: Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.
Gene ID
72562
Gene Name (Vector)
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Gene Symbol
Pcbd2
ORF Size (aa)
312
RefSeq ID
NM_028281
RefSeq Synonyms
NM_028281, BC028642,
Species
mouse
UniGene ID
Mm.28145

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.