mouse PBK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pbk.
shAAV-268120
AAV-m-PBK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pbk (PDZ binding kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810434B10Rik; AW538537; D14Ertd732e; TOPK
Description (Vector)
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Gene ID
52033
Gene Name (Vector)
PDZ binding kinase
Gene Symbol
Pbk
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_023209
RefSeq Synonyms
NM_023209, BC020099,
Species
mouse
UniGene ID
Mm.24337
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.