mouse PAPSS1 shRNA silencing AAV

Name
AAV-m-PAPSS1-shRNA

Cat No
shAAV-268050

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Papss1.

shAAV-268050

AAV-m-PAPSS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Papss1 (3′-phosphoadenosine 5′-phosphosulfate synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI325286; Asapk; SK1

Description (Vector)

Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

Gene ID

23971

Gene Name (Vector)

3'-phosphoadenosine 5'-phosphosulfate synthase 1

Gene Symbol

Papss1

ORF Size (aa)

1812

ORF Size (bp)

1812 bp

RefSeq ID

NM_011863

RefSeq Synonyms

NM_011863, NM_001289479, NM_001289478, NM_001289477, BC066055,

Species

mouse

UniGene ID

Mm.244912

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.