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mouse PAOX shRNA silencing AAV

Name 
AAV-m-PAOX-shRNA
Cat No 
shAAV-268038
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Paox.

shAAV-268038
AAV-m-PAOX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Paox (polyamine oxidase (exo-N4-amino)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2410012F02Rik; AI118225; Pao
Description (Vector)
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Gene ID
212503
Gene Name (Vector)
polyamine oxidase (exo-N4-amino)
Gene Symbol
Paox
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_153783
RefSeq Synonyms
NM_153783, NM_001346725, BC082783,
Species
mouse
UniGene ID
Mm.44197

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.