mouse PAIP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Paip1.
shAAV-268010
AAV-m-PAIP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Paip1 (polyadenylate binding protein-interacting protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PAIP-1
Description (Vector)
Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Gene ID
218693
Gene Name (Vector)
polyadenylate binding protein-interacting protein 1
Gene Symbol
Paip1
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
RefSeq ID
NM_145457
RefSeq Synonyms
NM_145457, NM_001079849, BC051042, BC019726,
Species
mouse
UniGene ID
Mm.132584
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.