mouse OMA1 shRNA silencing AAV

Name 
AAV-m-OMA1-shRNA
Cat No 
shAAV-267639
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Oma1.

shAAV-267639
AAV-m-OMA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Oma1 (OMA1 zinc metallopeptidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2010001O09Rik; MPRP-1; ZMPOMA1
Description (Vector)
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Gene ID
67013
Gene Name (Vector)
OMA1 zinc metallopeptidase
Gene Symbol
Oma1
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
RefSeq ID
NM_025909
RefSeq Synonyms
NM_025909, BC016238,
Species
mouse
UniGene ID
Mm.30021

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.