mouse OFD1 shRNA silencing AAV

Name
AAV-m-OFD1-shRNA

Cat No
shAAV-266339

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Ofd1.

shAAV-266339

AAV-m-OFD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ofd1 (oral-facial-digital syndrome 1 gene homolog (human)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Cxorf5; DXGgc7e; ORF2

Description (Vector)

Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis (By similarity).

Gene ID

237222

Gene Name (Vector)

oral-facial-digital syndrome 1 gene homolog (human)

Gene Symbol

Ofd1

ORF Size (aa)

3054

ORF Size (bp)

3054 bp

RefSeq ID

NM_177429

RefSeq Synonyms

NM_177429, BC120487, BC119070,

Species

mouse

UniGene ID

Mm.247480

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.