mouse NUDT21 shRNA silencing AAV

Name 
AAV-m-NUDT21-shRNA
Cat No 
shAAV-266190
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nudt21.

shAAV-266190
AAV-m-NUDT21-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nudt21 (nudix (nucleoside diphosphate linked moiety X)-type motif 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
25kDa; 3110048P04Rik; 5730530J16Rik; AU014860; AW549947; Cpsf5
Description (Vector)
Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.
Gene ID
68219
Gene Name (Vector)
nudix (nucleoside diphosphate linked moiety X)-type motif 21
Gene Symbol
Nudt21
ORF Size (aa)
684
ORF Size (bp)
684 bp
RefSeq ID
NM_026623
RefSeq Synonyms
NM_026623, BC090834, BC008270,
Species
mouse
UniGene ID
Mm.432611

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.