mouse NR3C2 shRNA silencing AAV

Name
AAV-m-NR3C2-shRNA

Cat No
shAAV-266055

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Nr3c2.

shAAV-266055

AAV-m-NR3C2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nr3c2 (nuclear receptor subfamily 3, group C, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Mlr; MR

Description (Vector)

Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

Gene ID

110784

Gene Name (Vector)

nuclear receptor subfamily 3, group C, member 2

Gene Symbol

Nr3c2

ORF Size (aa)

2943

ORF Size (bp)

2943 bp

RefSeq ID

NM_001083906

RefSeq Synonyms

NM_001083906, BC133713,

Species

mouse

UniGene ID

Mm.324393

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.