mouse NR2E3 shRNA silencing AAV

Name 
AAV-m-NR2E3-shRNA
Cat No 
shAAV-266049
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nr2e3.

shAAV-266049
AAV-m-NR2E3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nr2e3 (nuclear receptor subfamily 2, group E, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A930035N01Rik; PNR; rd7; RNR
Description (Vector)
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Gene ID
23958
Gene Name (Vector)
nuclear receptor subfamily 2, group E, member 3
Gene Symbol
Nr2e3
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_013708
RefSeq Synonyms
NM_013708, BC017521,
Species
mouse
UniGene ID
Mm.103641

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.