mouse NR2E1 shRNA silencing AAV

Name
AAV-m-NR2E1-shRNA

Cat No
shAAV-266048

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Nr2e1.

shAAV-266048

AAV-m-NR2E1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nr2e1 (nuclear receptor subfamily 2, group E, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

fierce; frc; Mtl1; Mtll; tailless; TLL; Tlx; XTLL

Description (Vector)

Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acic receptor (RAR) regulation in retinal cells.

Gene ID

21907

Gene Name (Vector)

nuclear receptor subfamily 2, group E, member 1

Gene Symbol

Nr2e1

ORF Size (aa)

1158

ORF Size (bp)

1158 bp

RefSeq ID

NM_152229

RefSeq Synonyms

NM_152229, BC057104,

Species

mouse

UniGene ID

Mm.287100

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.