mouse NR0B2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nr0b2.
shAAV-266031
AAV-m-NR0B2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nr0b2 (nuclear receptor subfamily 0, group B, member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SHP; SHP-1; Shp1
Description (Vector)
Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.
Gene ID
23957
Gene Name (Vector)
nuclear receptor subfamily 0, group B, member 2
Gene Symbol
Nr0b2
ORF Size (aa)
783
ORF Size (bp)
783 bp
RefSeq ID
NM_011850
RefSeq Synonyms
NM_011850, BC019540,
Species
mouse
UniGene ID
Mm.346759
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.