mouse NPLOC4 shRNA silencing AAV

Name 
AAV-m-NPLOC4-shRNA
Cat No 
shAAV-265990
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nploc4.

shAAV-265990
AAV-m-NPLOC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nploc4 (NPL4 homolog, ubiquitin recognition factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AK129375; mKIAA1499; Npl4
Description (Vector)
The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).
Gene ID
217365
Gene Name (Vector)
NPL4 homolog, ubiquitin recognition factor
Gene Symbol
Nploc4
ORF Size (aa)
1731
ORF Size (bp)
1731 bp
RefSeq ID
NM_199469
RefSeq Synonyms
NM_199469, NM_001195023, BC065156,
Species
mouse
UniGene ID
Mm.309520

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.