mouse NPC1 shRNA silencing AAV

Name 
AAV-m-NPC1-shRNA
Cat No 
shAAV-265968
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Npc1.

shAAV-265968
AAV-m-NPC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Npc1 (Niemann-Pick type C1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A430089E03Rik; C85354; D18Ertd139e; D18Ertd723e; lcsd; nmf164; spm
Description (Vector)
Involved in the intracellular trafficking of cholesterol. May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals.
Gene ID
18145
Gene Name (Vector)
Niemann-Pick type C1
Gene Symbol
Npc1
ORF Size (aa)
3834
ORF Size (bp)
3834 bp
RefSeq ID
NM_008720
RefSeq Synonyms
NM_008720, BC054539, BC052437,
Species
mouse
UniGene ID
Mm.3484

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.