mouse NMNAT2 shRNA silencing AAV

Name
AAV-m-NMNAT2-shRNA

Cat No
shAAV-265882

Availability
Immediate

This is an AAV expressing shRNA for silencing of Mouse Nmnat2.

shAAV-265882

AAV-m-NMNAT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nmnat2 (nicotinamide nucleotide adenylyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI843915; D030041I09Rik; PNAT1; PNAT2

Description (Vector)

Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannnot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).

Gene ID

226518

Gene Name (Vector)

nicotinamide nucleotide adenylyltransferase 2

Gene Symbol

Nmnat2

ORF Size (aa)

924

ORF Size (bp)

924 bp

RefSeq ID

NM_175460

RefSeq Synonyms

NM_175460, BC089007,

Species

mouse

UniGene ID

Mm.40548

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.