mouse NKX2-1 shRNA silencing AAV

Name 
AAV-m-NKX2-1-shRNA
Cat No 
shAAV-265812
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse NKX2-1.

shAAV-265812
AAV-m-NKX2-1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse NKX2-1 (NK2 homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AV026640; Nkx2.1; T/EBP; Titf1; Ttf-1
Description (Vector)
Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.
Gene ID
21869
Gene Name (Vector)
NK2 homeobox 1
Gene Symbol
NKX2-1
ORF Size (aa)
1119
RefSeq ID
NM_009385
RefSeq Synonyms
NM_009385, NM_001146198, BC080868, BC057607,
Species
mouse
UniGene ID
Mm.89972

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.