mouse NEIL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Neil2.
shAAV-265639
AAV-m-NEIL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Neil2 (nei like 2 (E. coli)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Gm1212; NEH2
Description (Vector)
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Gene ID
382913
Gene Name (Vector)
nei like 2 (E. coli)
Gene Symbol
Neil2
ORF Size (aa)
834
ORF Size (bp)
834 bp
RefSeq ID
NM_201610
RefSeq Synonyms
NM_201610, BC115762,
Species
mouse
UniGene ID
Mm.239490
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.