mouse NDRG4 shRNA silencing AAV

Name 
AAV-m-NDRG4-shRNA
Cat No 
shAAV-265552
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ndrg4.

shAAV-265552
AAV-m-NDRG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ndrg4 (N-myc downstream regulated gene 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D8Bwg1337e; Ndr1-rs; Ndr4; R74996; SMAP-8
Description (Vector)
Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
Gene ID
234593
Gene Name (Vector)
N-myc downstream regulated gene 4
Gene Symbol
Ndrg4
ORF Size (aa)
1020
ORF Size (bp)
1020 bp
RefSeq ID
NM_145602
RefSeq Synonyms
NM_145602, NM_001195006, BC006595,
Species
mouse
UniGene ID
Mm.29846

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.