mouse NACA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Naca.
shAAV-265394
AAV-m-NACA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Naca (nascent polypeptide-associated complex alpha polypeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AL022831; AL024382; Gm1878; mKIAA0363; skNAC
Description (Vector)
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
Gene ID
17938
Gene Name (Vector)
nascent polypeptide-associated complex alpha polypeptide
Gene Symbol
Naca
ORF Size (aa)
648
RefSeq ID
NM_013608
RefSeq Synonyms
NM_013608, NM_001282976, NM_001113199, BC099375, BC083340,
Species
mouse
UniGene ID
Mm.3746
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.